Bitwise Files for First-Ever Uniswap ETF, Paving Way for Mainstream DeFi Access

Feb 6, 2026, 1:03 a.m. 17 sources positive

Key takeaways:

  • UNI's 15% drop post-filing suggests market skepticism over ETF approval odds.
  • Approval could set precedent for COMP, AAVE, and MKR as next DeFi ETF candidates.
  • Watch SEC's stance on UNI's security classification as the key regulatory hurdle.

In a landmark move for the cryptocurrency industry, Bitwise Asset Management has officially submitted an S-1 registration statement to the U.S. Securities and Exchange Commission (SEC) for a Uniswap exchange-traded fund (ETF). This filing, reported on November 15, 2024, represents the first attempt to create a regulated investment vehicle tracking the governance token of a decentralized finance (DeFi) protocol.

The proposed Bitwise Uniswap ETF aims to provide both institutional and retail investors with regulated exposure to UNI, the native governance token of the Uniswap decentralized exchange, through traditional brokerage accounts. This could fundamentally alter the accessibility of DeFi investments, bridging the gap between traditional finance and blockchain-based protocols. The San Francisco-based asset manager, which oversees approximately $2 billion in crypto assets and launched the first Bitcoin futures ETF in 2021, is leveraging a period of increased regulatory clarity for digital assets.

The filing initiates a formal SEC review process expected to last several months. It arrives amidst a shifting U.S. regulatory and political landscape, with the SEC and CFTC coordinating more closely on digital asset regulations through initiatives like "Project Crypto." Furthermore, the administration's stated goal of making the U.S. the "crypto capital" of the world has encouraged financial innovation. Coinbase Custody Trust Company is named as the intended custodian to securely hold the UNI tokens, though the ETF will not include staking functionality.

Uniswap is the largest decentralized exchange by trading volume, having facilitated over $1.5 trillion in cumulative transactions since its 2018 launch. The UNI token, with a circulating market capitalization of roughly $6 billion, allows holders to govern protocol development. The ETF's approval is not guaranteed, as the SEC has previously raised questions about whether governance tokens like UNI constitute securities. Bitwise's legal team is expected to argue for its non-security status based on Uniswap's decentralized nature.

Market analysts note that approval could set a precedent for other DeFi token ETFs, potentially for tokens like Compound (COMP), Aave (AAVE), and Maker (MKR). However, the filing coincides with significant market volatility, with UNI's price dropping roughly 15% in the 24 hours surrounding the news. Experts suggest that a successful ETF could enhance UNI's liquidity and reduce volatility over time by attracting more institutional capital.

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